Hepatoprotective properties of Commiphora opobalsamum ("Balessan"), a traditional medicinal plant of Saudi Arabia.
نویسندگان
چکیده
The hepatoprotective activity of an ethanolic extract of Commiphora opobalsamum ("Balessan") was investigated in rats by inducing hepatotoxicity with carbon tetrachloride:liquid paraffin (1:1). This extract has been shown to possess significant protective effect by lowering serum transaminase levels (serum glutamate oxaloacetate transaminase and serum glutamate pyruvate transaminase), alkaline phosphatase and bilirubin. Pretreatment with an extract of Balessan prevented the prolongation of the barbiturate sleeping time associated with carbon tetrachloride-induced liver damage in mice. On the other hand, CCl4-induced low-level nonprotein sulfhydryl concentration in the liver was replenished by the Balessan extract. These data suggest that the plant C. opobalsamum may act as an antioxidant agent and may have a hepatoprotective effect.
منابع مشابه
Antimicrobial activity of essential oil and methanol extract from Commiphora molmol (Engl.) resin
The genus Commiphora (Burseraceae) with more than 150 plant species, is distributed in the tropical and subtropical regions, especially occurring in northeastern Africa, southern Arabia and India (Langenheim, 2003). The plants of Commiphora species are characterized as small trees or shrubs with spinescent branches, pale-gray bark and reddishbrown resinous exudates. The resinous exudates of the...
متن کاملAn Evaluation of the Antimicrobial Activity of Commiphora myrrha Nees (Engl.) Oleo-gum Resins from Saudi Arabia
متن کامل
A Review of Hepatoprotective Plants Used in Saudi Traditional Medicine
Liver disease is one of the major causes of morbidity and mortality across the world. According to WHO estimates, about 500 million people are living with chronic hepatitis infections resulting in the death of over one million people annually. Medicinal plants serve as a vital source of potentially useful new compounds for the development of effective therapy to combat liver problems. Moreover ...
متن کاملSHPIS: A Database of Medicinal Plants from Saudi Arabia
Many studies in the past have revealed the use of the indigenous medicinal plant for the treatment of various diseases in Saudi Arabia. However, the details of these indigenous essential medicinal herbs and their therapeutic implication against various human and animals diseases are not well documented and organised in a local platform. In this regard, a thorough mining of scholarly article for...
متن کاملAssessment of phylogenetic relationship of rare plant species collected from Saudi Arabia using internal transcribed spacer sequences of nuclear ribosomal DNA.
The rare and endangered plants of any country are important genetic resources that often require urgent conservation measures. Assessment of phylogenetic relationships and evaluation of genetic diversity is very important prior to implementation of conservation strategies for saving rare and endangered plant species. We used internal transcribed spacer sequences of nuclear ribosomal DNA for the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Drugs under experimental and clinical research
دوره 30 5-6 شماره
صفحات -
تاریخ انتشار 2004